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No. 153
From wikipedia:
>Methadone has a typical elimination half-life of 15 to 60 hours with a mean of around 22. However, metabolism rates vary greatly between individuals, up to a factor of 100,[46][47] ranging from as few as 4 hours to as many as 130 hours,[48] or even 190 hours.[49] This variability is apparently due to genetic variability in the production of the associated enzymes CYP3A4, CYP2B6 and CYP2D6.
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