I'm thinking it should be more puzzle based than roll based. Depending on your skillset, your options will be fight, flight, trickery, or sorcery.
So I guess this could be where you pick your character's initial abilities.
It is common to have many death screens for every encounter in these types of games. For example, trying to swim away while still chained results in drowning, while attempting to join the furries results in a death screen "yiff in hell furfag." As per usual, the death screens bring up a reload prompt. These are actually most of the fun in an adventure game, so even if the game doesn't get made per se, we at least have a bunch of funny reaction images.
If you kill one of the furries and use the hide as a disguise, when you reach the next town you will be kill on sight, unless you make it to one of the most cancerous areas, where your normal countenance is kill on sight.
This is considered a "cancerous" action. Watch your cancer bar up top, if it fills up, cancer will metastasize in your body and an identical copy of you will burst forth (like in army of darkness), with exactly your abilities, which you need to fight. If playing on the lowest difficulty, if you lose to your clone it isn't game over, but at the end of your name will be added "The Faggot," and everyone will call you by your full name.
"Cleansing" actions will reduce your cancer level, as well as certain consumables, herb etc.